Mikhaleva Elena Anatolievna | Institute of Molecular Genetics
Academic degree:
Doctor of Philosophy (Biology)

Academic title:
without academic rank


Division of IMG:
Laboratory of biochemical genetics of animals

Position:
Researcher


Telephone:
+7-499-196-71-83

Е-mail:
lenamikh@img.ras.ru



Main research interests

-Study of protein-protein interactions involved in the suppression of transposons in the genome by the example of the functioning of one of the participants of the process of RNA interference-protein PIWI. 
-The link between  functional activity of genes  and the spatial organization of the chromosomes in the cell nucleus on the model object-drosophila, as well as in Drosophila cell culture.


Publications

  1. [Glycoproteins from Drosophila melanogaster cell culture contains O-bound carbohydrate chains of the Gal(beta1-3)GalNAc type]. Kramerov AA, Arbatskiĭ NP, Rozovskiĭ IaM, Pochechueva TI, Mikhaleva EA, Druzhinina TI, Gvozdev VA, Shibaev VN. Biokhimiia. 1995 May;60(5):805-12. Russian.
  2. Mucin-type glycoprotein from Drosophila melanogaster embryonic cells: characterization of carbohydrate component. Kramerov AA, Arbatsky NP, Rozovsky YM, Mikhaleva EA, Polesskaya OO, Gvozdev VA, Shibaev VN. FEBS Lett. 1996 Jan 15;378(3):213-8.
  3. Insect mucin-type glycoprotein: immunodetection of the O-glycosylated epitope in Drosophila melanogaster cells and tissues. Kramerov AA, Mikhaleva EA, Rozovsky Ya M, Pochechueva TV, Baikova NA, Arsenjeva EL, Gvozdev VA. Insect Biochem Mol Biol. 1997 Jun;27(6):513-21.
  4. [The tissue localization and secretion of mucin-D in Drosophila melanogaster]. Kramerov AA, Mikhaleva EA, Pochechueva TV, Rozovskiĭ IaM, Baĭkova NA, Gvozdev VA. Ontogenez. 1997 Jul-Aug;28(4):279-87. Russian.
  5. [The interplay of transposon silencing genes in the Drosophila melanogaster germline]. Sokolova OA, Iakushev EIu, Stoliarenko AD, Mikhaleva EA, Gvozdev VA, Klenov MS. Mol Biol (Mosk). 2011 Jul-Aug;45(4):633-41. Russian.
  6. Separation of stem cell maintenance and transposon silencing functions of Piwi protein. Klenov MS, Sokolova OA, Yakushev EY, Stolyarenko AD, Mikhaleva EA, Lavrov SA, Gvozdev VA. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18760-5. doi: 10.1073/pnas.1106676108. Epub 2011 Nov 7.
  7. Role of histone deacetylases in gene regulation at nuclear lamina. Milon BC, Cheng H, Tselebrovsky MV, Lavrov SA, Nenasheva VV, Mikhaleva EA, Shevelyov YY, Nurminsky DI. PLoS One. 2012;7(11):e49692. doi: 10.1371/journal.pone.0049692. Epub 2012 Nov 30.
  8. [Essential functions of microRNAs in the reproductive organs of animals]. Ryazansky SS, Mikhaleva EA, Olenkina OM. Mol Biol (Mosk). 2014 May-Jun;48(3):371-85. Review. Russian.
  9. [PIWI protein as a nucleolus visitor in Drosophila melanogaster]. Mikhaleva EA, Iakushev EIu, Stoliarenko AD, Klenov MS, Pozovskiĭ IaM, Gvozdev VA. Mol Biol (Mosk). 2015 Jan-Feb;49(1):184-9. Russian.