Klimuk Evgeny Ivanovich | Institute of Molecular Genetics


Academic degree:
Doctor of Philosophy (Biology)

Academic title:
without academic rank


Division of IMG:
Laboratory regulation of gene expression of microorganisms

Position:
Researcher


Telephone:
+7-499-196-18-52

Е-mail:


Main research interests

Transcription regulation, transcription factors, inhibitors of RNA-polymerase, bacteriophages, viral DNA packaging, DNA-protein interactions.


Publications

  1. Esyunina D, Klimuk E, Severinov K, Kulbachinskiy A. Distinct pathways of RNA polymerase regulation by a phage-encoded factor. P Natl Acad Sci USA. 2015 17;112(7):2017-22
  2. Ceyssens PJ, Minakhin L, Van den Bossche A, Yakunina M, Klimuk E, Blasdel B, De Smet J, Noben JP, Bläsi U, Severinov K, Lavigne R. Development of Giant Bacteriophage ϕKZ Is Independent of the Host Transcription Apparatus. J Virol. 2014;88(18):10501-10
  3. Klimuk E, Akulenko N, Makarova KS, Ceyssens PJ, Volchenkov I, Lavigne R, Severinov K. Host RNA polymerase inhibitors encoded by phiKMV-like phages of Pseudomonas. Virology. 2013;436(1):67-74
  4. Pavlova O., Lavysh D., Klimuk E., Djordjevic M., Ravcheev D. A., Gelfand M. S., Severinov K., Akulenko N., Temporal regulation of gene expression of the Escherichia coli bacteriophage phiEco32. J Mol Biol. 2012;416(3):389-99.
  5. Graf A, Kabysheva M, Klimuk E, Trofimova L, Dunaeva T, Zündorf G, Kahlert S, Reiser G, Storozhevykh T, Pinelis V, Sokolova N, Bunik V. Role of 2-oxoglutarate dehydrogenase in brain pathologies involving glutamate neurotoxicity. Journal of Molecular Catalysis B: Enzymatic 61 (2009) 80–87.
  6. Bunik V, Kabysheva M, Klimuk E, Storozhevykh T, Pinelis V. Phosphono analogues of 2-oxoglutarate protect cerebellar granule neurons upon glutamate excitotoxicity. Ann N Y Acad Sci. 2009;1171:521-9.