Inozemtseva Lyudmila Sergeevna | Institute of Molecular Genetics
Academic degree:
without a degree

Academic title:
without academic rank


Division of IMG:
Laboratory of molecular genetics of somatic cells

Position:
Junior Researcher


Telephone:
+7-499-196-02-11

Е-mail:
lsi@img.ras.ru



Main research interests

The research is related to effects of endogenous and synthetic melanocortin peptides on the magnitude of the stress and inflammatory responses. The research is also directed to study the effects of melanocortins on expression of neurotrophic factors in the rat brain in vivo and in primary and transformed brain cell cultures.


Publications

  1. Shadrina M.I., Dolotov O.V., Grivennikov I.A., Inozemtseva L.S., Andreeva L.A., Slominsky P.A., Limborska S.A., Myasoedov N.F.. Rapid induction of neurotrophin mRNAs in rat glial cell cultures by Semax, an adrenocorticotropic hormone analog. Neurosci. Lett. 2001, 308, 115-118.
  2. Novosadova E.V., Manuilova E.S., Arsen'eva E.L., Khaidarova N.V, Dolotov O.V., Inozemtseva L.S., Kozachenkov K.Y., Tarantul V.Z., Grivennikov I.A. Different effects of enhanced and reduced expression of pub gene on the formation of embryoid bodies by cultured embryonic mouse stem cell. Bull. Exp. Biol. Med. 2005, 140, 1, 153-158.
  3. Zolotarev Iu.A., Dadaian A.K., Dolotov O.V. et al. Evenly tritium-labeled peptides and their in vivo and in vitro biodegradation. Bioorg. Khim. 2006, 32, 2, 183-191.
  4.  Dolotov O.V., Karpenko E.A., Seredenina T.S., Inozemtseva L.S., Levitskaya N.G., Zolotarev Yu.A., Kamensky A.A., Grivennikov I.A., Engele J., Myasoedov N.F.. Semax, an analogue of adrenocorticotropin (4–10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain. J. of Neurochem. 2006, 97, s1, 82-86.
  5. Zolotarev Yu.A., Dolotov O.V., Inozemtseva L.S., Dadayan A.K., Dorokhova E.M., Andreeva L.A., Alfeeva L.Yu., Grivennikov I.A., Myasoedov N.F.. Degradation of the ACTH(4-10) analog Semax in the presence of rat basal forebrain cell cultures and plasma membranes. Amino Acids. 2006, 30, 4, 403-408.
  6. Dolotov O.V., Karpenko E.A., Inozemtseva L.S., Seredenina T.S., Levitskaya N.G., Rozyczka J., Dubynina E.V., Novosadova E.V., Andreeva L.A., Alfeeva L.Y., Kamensky A.A., Grivennikov I.A., Myasoedov N.F., Engele J. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Research. 2006, 1117, 1, 54-60.
  7. . Inozemtseva L.S., Karpenko E.A., Dolotov O.V. Levitskaya N.G., Kamensky A.A., Andreeva L.A., Grivennikov I.A. Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo. Dokl. Biol. Sci. 2008, 421, 241-243.
  8.  E.S. Manuilova, E.L. Arsenyeva, N.V. Khaidarova, I.N. Shugurova, L.S. Inozemtseva, V.Z. Tarantul, I.A. Grivennikov. Different effects of regulatory genes (tat, nef) of human immunodeficiency virus type 1 (HIV-1) on the proliferation and differentiation of mouse embryonic stem cells in vitro. Int. J. Biomed. Sci. 2008, V. 4, № 1, P. 100-108.
  9.  Dubynina E.V., Inozemtseva L.S., Markov D.D., Yatsenko K.A., Dolotov O.V., Grivennikov I.A. Neurochem. J. 2009, 3, 4, 267-271.
  10. Glazova N.Y., Atanov M.S., Pyzgareva A.V., Andreeva L.A., Manchenko D.M., Markov D.D.,  Inozemtseva L.S., Dolotov O.V., Levitskaya N..G., Kamensky A.A., Grivennikov I.A., Myasoedov N.F. Neurotropic activity of ACTH(7-10)PGP, an analog of an ACTH fragment. Dokl. Biol. Sci. 2011, 440, 270-274.
  11.  Volodina M.A., Sebentsova E.A., Glazova N.Y., Manchenko D.M. Inozemtseva L.S., Dolotov O.V., Andreeva L.A., Levitskaya N.G., Kamensky A.A., Myasoedov N.F. Correction of long-lasting negative effects of neonatal isolation in white rats using semax. Acta Naturae. 2012, 4, 1, 86-92.
  12.  Yatsenko K.A., Glazova N.Y., Inozemtseva L.S., Andreeva L.A., Kamensky A.A., Grivennikov I.A., Levitskaya N.G., Dolotov O.V., Myasoedov N.F. Heptapeptide semax attenuates the effects of chronic unpredictable stress in rats. Dokl. Biol. Sci. 2013, 453, 353-357.