Fedoseyeva Viya Borisovna | Institute of Molecular Genetics

Academic degree:
Doctor of Philosophy (Biology)

Academic title:
without academic rank

Division of IMG:
Laboratory of bioinformatics




Main research interests

The basic works are devoted the development of methods for the study of genetic material, the analysis of structural and functional analysis of DNA/RNA and their complexes with proteins, the development of the theoretical foundations of modern bioinformatics with a focus on the study of diseases associated with deletions. The results were published in more than 25 publications.
 1976-1990. A series of studies on the development of methods of electronic microscopy and DNA complexes with proteins, spectrometry methods for studying transcription.
 1991-1996. Theoretical and experimental study the flexibility of DNA fragments have been identified and studied flexible oligonucleotides associated with pauses of transcription.
 1996-2016. Methods of bioinformatics included the creation of the software package for nucleosomal positioning, localization of repressive complexes, to study the secondary structure of RNA products of long introns.


1. Fedoseyeva V.B., Alexandrov A.A. Small circles of helical DNA obtained on the basis of transcription pause sites sequence . J. Biomol. Struct. Dyn., 1998, 15, 1167-1172.
2. Fedoseeva V.B., Alexandrov A.A., Korobko V.G., Nekrasova O.V., Klinov D.V. Structural investigation of flexible DNA. J. Biomol. Struct. Dynamics, 2001, 18, 893.
3. Fedoseyeva V.B., Alexandrov A.A. Analysis and development of the computer methods of nucleosome localization on DNA fragments with different AT-content. J. Biomol. Struct. Dyn., 2007, 24, 481-488.
4. Fedoseyeva V.B., Alexandrov A.A. Large-scale periodicity of nucleosome positioning signal in pericentric regions of chromosomes (Drosophila melanogaster).  (2014). Journal of Biomolecular Structure and Dynamics, V.32, P.2042-2050. http://dx.doi.org/10.1080/07391102.2013.844081                                                                                                                                        
5. FedoseyevaV., Zharinova I., Alexandrov A. Secondary structure stretched forms of long intron RNA products  from the view point of initiation of chromosome homologs somatic pairing. (2015). Journal of Biomolecular Structure and Dynamics  V.33, P.869-876. http://dx.doi.org/10.1080/07391102.2014.917361
6. Федосеева В.Б Theoretical evaluation of the nucleosomal density at the gene sequences of different orthologs upon euchromatin and heterochromatic localization.(2014) Mathematical biology and bioinformatics. V. 9. № 1. P.273 –285.
7,   Fedoseyeva Viya. Types of self-assembling of lengthy intron RNA presented in the regions of homologous chromosomes somatic pairing.  4th International Conference on Nanotek&Expo December 01-03, 2014 OMICS Group Conferences,  J.Nanomed Nanotechnol, 2014, vol.5, Issue 5,  http://dx.doi.org/10.4172/2157-7439.S1.017 (доклад)